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Homepage > Forlax® 10g

Forlax® OTC Constipation Medicine

 

Forlax® for adults and children 8 years old and above

An osmotic laxative and a trusted option against constipation.
Forlax® 10g is a powder for oral solution. It contains Macrogol 4000 (Polyethylene Glycol / PEG 4000).

 

  • An effective solution used by doctors, pharmacists and patients with more than twenty years of experience.1-3

  • Forlax® (Macrogol 4000) is a highly recommended therapeutic option in international guidelines.3-4

  • A trusted solution with demonstrated efficacy in clinical studies, reviews and in meta-analyses.2-10

  • A solution for patients: adults, seniors, children aged 8 years and above.2-3, 11

  • Well tolerated.2

How Forlax® works

 

  • Forlax® acts by binding water and retaining it in the intestine, thus increasing stool hydration.12

  • This softens the stools and increases their volume.12

  • The instestine can move the stools easily again and the bowel movement is facilitated and occure naturally.12

 

Preferably taken as a single dose in the morning

Dosage and administration13

The effect of Forlax® 10g becomes apparent within 24 to 48 hours after its administration.

Forlax® 10g should not be used as self-medication for more than 2 weeks. If symptoms persist, medical advice should be sought.

 

Product warnings and indications13

Pregnancy

Take this medication during pregnancy only after consultation with a doctor. If you discover that you are pregnant during treatment, consult your doctor who will decide on the need to continue treatment.

 

Breast feeding

There are no data on the excretion of Forlax® in breastmilk. As Macrogol 4000 is not significantly absorbed, Forlax® may be administered during breast feeding.

 

Like all medicines, Forlax® can  have side effects. Possible side effects include:

  1. Very high dose may cause diarrhea. In this case, you should discontinue the treatment or reduce the dosage. The symptom of diarrhea will disappear within 24 to 48 hours of discontinuing treatment. You may resume the treatment with Forlax® 10g at a lower dose.
  2. In very rare cases, allergic type reactions such as rash, itching and swelling may happen.
  3. Other reported side effects are bloating, abdominal pain, nausea, vomiting and borborgym (growling noise in the tummy).

Forlax® Patient Information Leaflet (pdf, 1 MB)

References:
1. Higgins PD, Johanson JF. Epidemiology of constipation in North America: a systematic review. Am J Gastroenterol. Apr 2004;99(4):750 759.
2. Chassagne P, Ducrotte P, Garnier P, Mathiex Fortunet H. Tolerance and Long Term Efficacy of Polyethylene Glycol 4000 (Forlax(R)) Compared to Lactulose in Elderly Patients with Chronic Constipation. J Nutr Health Aging. 2017;21(4):429 439.
3. Tabbers MM, DiLorenzo C, Berger MY, et al. Evaluation and treatment of functional constipation in infants and children: evidence based recommendations from ESPGHAN and NASPGHAN. J Pediatr Gastroenterol Nutr . Feb 2014;58(2):258 274.
4. American Gastroenterological Association. Bharucha AE, Dorn SD, Lembo A, Pressman A. American Gastroenterological Association medical position statement on constipation. Gastroenterology. Jan 2013;144(1):211 217.
5. Suares NC, Ford AC. Prevalence of, and risk factors for, chronic idiopathic constipation in the community: systematic review and meta analysis. Am J Gastroenterol. Sep 2011;106(9):1582 1591; quiz 1581, 1592.
6. Peppas G, Alexiou VG, Mourtzoukou E, Falagas ME. Epidemiology of constipation in Europe and Oceania: a systematic review. BMC Gastroenterol. Feb 12 2008 ;8:
7. Mugie SM, Benninga MA, Di Lorenzo C. Epidemiology of constipation in children and adults: a systematic review. Best Pract Res Clin Gastroenterol. Feb 2011;25(1):3 18.
8. Lindberg G, et al. J Clin Gastroenterol 2011;45(6):483-7. Rao SSC, et al.. Nat Rev Gastroenterol Hepatol 2016;13(5):295-305. Suares NC, Ford AC. Am J Gastroenterol
2011;106:1582-91.
9. Belsey JD, Geraint M, Dixon TA. Systematic review and meta analysis : polyethylene glycol in adults with non organic constipation. Int J Clin Pract . Jun 2010;64(7):944 955.
10. Lee Robichaud H, Thomas K, Morgan J, Nelson RL. Lactulose versus Polyethylene Glycol for Chronic Constipation. Cochrane Database Syst Rev. Jul 7 2010(7):CD007570.
11. Dupont C, et al. Double blind randomized evaluation of clinical and biological tolerance of polyethylene glycol 4000 versus lact ulose in constipated children. J Pediatr Gastroenterol Nutr 2005;41:625 33
12.Hudziak H, Bronowicki JP, Franck P, Dubos Berogin C, Bigard MA. [ Lowdose polyethylene glycol 4000: digestive effects. Randomized doubleblind study in healthy subjects]. Article in
French. Gastroenterol Clin Biol. 1996;20(5):418 423.
13. Forlax (Patient Information Leaflet). Singapore: IPSEN; Date of revision of text: Aug 2019